zenCELL Owl

The wound healing, migration or scratch assay is a popular method to analyse cell migration in vitro. The dynamics of cell migration into a cell-free area, which has been created by direct manipulation or physical exclusion, are monitored and quantified.

· Capture and analyse dynamic changes at 5 minute intervals over several days

· Observe and control every timepoint and step of the wound-healing process retrospectively and in detail

· Calculate the speed of wound healing by analysing the increase of confluence in the gap area

· Simultaneously analyse 24 wells under identical conditions, improving the comparability and reproducibility of your data Scratch Assay Application Note zencell-owl_Application-Note-Scratch-Assay.pdf (zencellowl.com)

Cytotoxicity assays are widely used in vitro to predict tissue-specific toxicity or to identify leads for anti-cancer therapies. It is a fundamental tool in the drug discovery process. The zenCELL owl allows long-term monitoring of dynamic changes in cell morphology as the result of drug treatment

· Evaluate the cytotoxic effect of different agents / treatments on up to 24 cell cultures simultaneously and over the long-term

· Automated and around the clock data capture, enables every timepoint of your cytotoxicity assay to be analysed retrospectively and in detail

· Observe changes to morphology and confluence from outside the lab

· Create defined and stable environmental conditions for your cell culture in the incubator

· Analyse dynamic changes on a single cell level and document changes with time lapse videos

· Compare different drugs or drug concentrations under identical environmental conditions in an automated and non-invasive way Cytotoxicity Application Note zencell-owl_Analysis-of-Cytostatic-Drug-Effects.pdf (zencellowl.com)

Spheroids have become an established tissue model for health and disease. These mimic in vivo like conditions and better simulate cell-cell, cell-matrix and cell-drug interactions than single cell or monolayer models. The zenCELL owl is a valuable tool in the monitoring of spheroid development and proliferation Spheroid Imaging Application Note zencell-owl_Application-Note-Time-lapse-imaging-of-spheroids.pdf (zencellowl.com)